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Search Results for " allergic rhinitis "

20

Compounds

Cat No. Product Name Synonyms Targets
T8239 Cromoglicic acid Others
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
T4S0878 Prunetin Prunusetin ERK , Dehydrogenase , NF-κB
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...
T0211 Azelastine Azelastina,Astelin,Azelastinum SARS-CoV , Histamine Receptor
Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.
T3979 Emedastine LY188695,Emadine Histamine Receptor
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its...
T21404 Fluticasone furoate Veramyst,Allermist,Avamys,Fluticasone furoate Glucocorticoid Receptor
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure...
T0118 Mizolastine SL 850324 Histamine Receptor
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives.
T4038 Ectoine THP(B),L-Ectoine Others , Antibacterial
Ectoine (L-Ectoine) is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as E.coli.
T6242 Rupatadine Fumarate Rinialer,Rupafin,Alergoliber PAFR , Autophagy , Histamine Receptor
Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.
T0059 Diphenylpyraline hydrochloride 4-Diphenylmethoxy-1-methylpiperidine hydrochloride Histamine Receptor
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re...
T3185 R112 (E)-Elafibranor Syk
R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.
T1030 Triprolidine hydrochloride monohydrate Triprolidine hydrochloride Histamine Receptor
Triprolidine hydrochloride monohydrate is a histamine H1 antagonist used in allergic rhinitis, asthma.
T0211L Azelastine hydrochloride Optivar,Azelastine HCl,Allergodil,Astelin SARS-CoV , Histamine Receptor
Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity.
T1269 Tripelennamine hydrochloride Pyribenzamine hydrochloride,Tripelennamine HCl,Pyribenzamine HCl Histamine Receptor
Tripelennamine hydrochloride (Pyribenzamine hydrochloride) is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation.
T2335 Ebastine Ebastel,LAS-W 090,Ebastin,Kestine,RP64305 Histamine Receptor
Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss...
T0188 Fluticasone (propionate) CCI-187881,Fluticasone propionate Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
T0205 Brompheniramine maleate Dimotane,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane 5-HT Receptor , Histamine Receptor
Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.
T0089 Cetirizine dihydrochloride P071,UCB P071,Cetirizine DiHCl Histamine Receptor
Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventiona...
T6660 SB-705498 TRP/TRPV Channel
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
T1470 Fexofenadine hydrochloride Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,Telfast,Fexofenadine HCl,Allegra,MDL 16455A Histamine Receptor
Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria.
T1553 Chlorpheniramine maleate NCI-C55265,Chlorphenamine maleate Histamine Receptor
Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.

Compounds

Cromoglicic acid
T8239
Synonym:
Target: Others
Prunetin
T4S0878
Synonym: Prunusetin
Target: ERK, Dehydrogenase, NF-κB
Azelastine
T0211
Synonym: Azelastina,Astelin,Azelastinum
Target: SARS-CoV, Histamine Receptor
Emedastine
T3979
Synonym: LY188695,Emadine
Target: Histamine Receptor
Fluticasone furoate
T21404
Synonym: Veramyst,Allermist,Avamys,Fluticasone furoate
Target: Glucocorticoid Receptor
Mizolastine
T0118
Synonym: SL 850324
Target: Histamine Receptor
Ectoine
T4038
Synonym: THP(B),L-Ectoine
Target: Others, Antibacterial
Rupatadine Fumarate
T6242
Synonym: Rinialer,Rupafin,Alergoliber
Target: PAFR, Autophagy, Histamine Receptor
Diphenylpyraline hydrochloride
T0059
Synonym: 4-Diphenylmethoxy-1-methylpiperidine hydrochloride
Target: Histamine Receptor
R112
T3185
Synonym: (E)-Elafibranor
Target: Syk
Triprolidine hydrochloride monohydrate
T1030
Synonym: Triprolidine hydrochloride
Target: Histamine Receptor
Azelastine hydrochloride
T0211L
Synonym: Optivar,Azelastine HCl,Allergodil,Astelin
Target: SARS-CoV, Histamine Receptor
Tripelennamine hydrochloride
T1269
Synonym: Pyribenzamine hydrochloride,Tripelennamine HCl,Pyribenzamine HCl
Target: Histamine Receptor
Ebastine
T2335
Synonym: Ebastel,LAS-W 090,Ebastin,Kestine,RP64305
Target: Histamine Receptor
Fluticasone (propionate)
T0188
Synonym: CCI-187881,Fluticasone propionate
Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite
Brompheniramine maleate
T0205
Synonym: Dimotane,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane
Target: 5-HT Receptor, Histamine Receptor
Cetirizine dihydrochloride
T0089
Synonym: P071,UCB P071,Cetirizine DiHCl
Target: Histamine Receptor
SB-705498
T6660
Synonym:
Target: TRP/TRPV Channel
Fexofenadine hydrochloride
T1470
Synonym: Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,Telfast,Fexofenadine HCl,Allegra,MDL 16455A
Target: Histamine Receptor
Chlorpheniramine maleate
T1553
Synonym: NCI-C55265,Chlorphenamine maleate
Target: Histamine Receptor
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TargetMol